PROTOCOL
WHAT IS THERAPEUTIC FASTING?
Therapeutic fasting is a method in which a person voluntarily refrains from ingesting solid foods to live off their reserves, basically fat reserves, for a specific period of time.
As a result, autophagy is stimulated and detoxifying enzymes are activated, producing a deep cleaning of cells and tissues. At the same time, fasting reduces inflammatory processes, thereby relieving pain and mobility limitations.
A DAY OF FASTING
LOOKS LIKE THIS
SCIENTIFIC BASES
List of scientific sources on therapeutic fasting, efficacy and safety.
- 1.- Wilhelmi de Toledo F, Grundler F, Bergouignan A, Drinda S, Michalsen A (2019) Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects. PLOS ONE 14(1): e0209353. https://doi.org/10.1371/journal.pone.0209353
- 2.- Drinda, S.; Grundler, F.; Neumann, T.; Lehmann, T.; Steckhan, N.; Michalsen, A.; Wilhelmi de Toledo, F. Effects of Periodic Fasting on Fatty Liver Index—A Prospective Observational Study. Nutrients 2019, 11, 2601. https://www.mdpi.com/2072-6643/11/11/2601
- 3.- Grundler F, Mesnage R, Ruppert PMM, Kouretas D, Wilhelmi de Toledo F. Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety. Nutrients. 2024; 16(12):1849. https://doi.org/10.3390/nu16121849
- 4.- Franziska Gründler, Marcella Palumbo, Maria Pia Adorni, Francesca Zimetti, Bianca Papotti, Dietmar Plonné, Alfred Holley, Robin Mesnage, Massimiliano Ruscica, Françoise Wilhelmi de Toledo, - HDL cholesterol efflux capacity and cholesterol loading capacity in long-term fasting: Evidence from a prospective, single-arm interventional study in healthy individuals, Atherosclerosis, https://doi.org/10.1016/j.atherosclerosis.2024.118548
- 5.- Laurens C., Grundler F., Damiot A., Chery I., Le Maho A.-L., Zahariev A., Le Maho Y., Bergouignan A., Gauquelin-Koch G., Simon C., Blanc S., and Wilhelmi de Toledo F. (2021) Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations, Journal of Cachexia, Sarcopenia and Muscle, 12, 1690–1703, https://doi.org/10.1002/jcsm.12766
- 6.- Grundler, F., Séralini, G. E., Mesnage, R., Peynet, V., & Wilhelmi de Toledo, F. (2021). Excretion of Heavy Metals and Glyphosate in Urine and Hair Before and After Long-Term Fasting in Humans. Frontiers in nutrition, 8, 708069. https://doi.org/10.3389/fnut.2021.708069
- 7.- Wilhelmi de Toledo F, Grundler F, Goutzourelas N, Tekos F, Vassi E, Mesnage R, Kouretas D. Influence of Long-Term Fasting on Blood Redox Status in Humans. Antioxidants. 2020; 9(6):496. https://doi.org/10.3390/antiox9060496